Overview |
Speakers |
Programme |
Sponsors |
Registration/Abstracts |
Location/Travel |
Accommodation |
Organisers/Contact |
Programme
An overview of the programme for the conference can be viewed below. As speakers are confirmed, details will be added to the programme. Here is some other practical information regarding the schedule of the conference.
- The conference will open on at 14:00 on Monday the 5th of June and end at 12:30 on Wednesday the 7th of June.
- The conference will take place at the Patio de la Infanta, Zaragoza.
- Participants are invited to a conference dinner on the evening of the 6th of June.
- For MOSBRI partners only, the general assembly will take place on the afternoon of the 7th June, starting at 14:00.
6th June 2023: The updated book of abstracts, including some practical information about the conference, is available for download. Last updated: 06/06-2023
MOSBRI2023-BookOfAbstracts-Zaragoza-June2023_20230606.pdf
Monday 5th June 2023
| 13:30 | Welcome coffee | |
| 14:00 | Opening/Welcome | |
| SESSION 1: Protein stability, quality control and standards | ||
| Organisers: EMBL-SPC, EMBL, Hamburg, DE and AU-SRCD, Aarhus University, Aarhus, DK | ||
| Chair(s): María García (EMBL-SPC), Søren Vrønning Hoffmann (AU-SRCD, Aarhus, DK) | ||
| 14:15 | Functional and structural characterization of Bone Morphogenetic Protein- 2 and the antagonist Noggin Andre Matagne University of Liège, Belgium | Talk |
| 14:40 | How and why do we develop standard proteins? Maelenn Chevreuil Molecular Biophysics, Institut Pasteur, Paris, France | Talk |
| 15:05 | Circular dichroism as a tool to monitor real-time structural changes in monoclonal antibody manufacture Maria Gabriela Bruque School of Biosciences, University of Birmingham, UK | TNA beneficiary |
| 15:20 | Elucidating Interactions Between SARS-CoV-2 proteins Jacek Plewka Jagiellonian University, Poland | TNA beneficiary |
| 15:35 | SUPR-DSF – Differential Scanning Fluorimetry for high-throughput protein stability screening Jemma Roberts Applied Photophysics | Company presentation |
| 15:45 | Ultimate DSC : a new tool for protein characterization Yannice Ricci Calneos | Company presentation |
| 15:55 | Coffee break | |
| SESSION 2 Redesigning Biomolecules to improve performance | ||
| Organisers: Malvern, Malvern, UK and BIFI-LACRIMA, University of Zaragoza, Zaragoza, ES | ||
| Chair(s): Natalia Markova (MALVERN) and Adrián Velázquez-Campoy (BIFI-LACRIMA) | ||
| 16:30 | Tuning protein stability through charged mutations and multivalent excipients Matja Zalar University of Maribor, Slovenia | Talk |
| 16:55 | Protein stabilization made simple: new bioinformatics tools for stability design Javier Sancho University of Zaragoza, Spain | Talk |
| 17:20 | Characterization of the redox-centres in the electron-confurcating [FeFe]-Hydrogenase (HydABC) of Thermotoga maritima Kilian Zuchan Aix-Marseille Université, CNRS, France | TNA beneficiary |
| 17:35 | Experimental evidence of intrinsic disorder and amyloid formation by the Henipavirus W proteins Giulia Pesce Marseille, France | Selected poster |
| 17:50 | Specific Extracellular Vesicle detection and isolation in complex samples using FO-SPR Kris Ver Donck Fox Biosystems | Company presentation |
| 18:00 | How to characterize the mode of action and avidity effects of antibodies using switchSENSE® and RT-IC Amandine Gontier Dynamic Biosensors | Company presentation |
| 18:10 | Poster / networking session and cocktail dinner |
Tuesday 6th June 2023
| 08:30 | Welcome coffee | |
| SESSION 3 Macromolecular interactions: kinetics and thermodynamics | ||
| Organisers: ISMB-BIOPHYSX, Birkbeck College, University of London, London, UK and BIFI-LACRIMA, University of Zaragoza, Zaragoza, ES | ||
| Chair(s): Mark Williams (ISMB-BIOPHYSX) and Maria Sunnerhagen (ProLinC) | ||
| 09:00 | Intrinsically disordered regions in proteins: Implications for physiology and drug discovery Adrián Velázquez-Campoy University of Zaragoza, Spain | Talk |
| 09:25 | Four different biophysical methods and simulations reveal that protein quaternary structures in solution are a mixture of multiple forms Gideon Schreiber Weizmann Institute of Science, Israel | Talk |
| 09:50 | Characterization of the interaction of monoclonal antibodies with bacterial GAPDH Pedro Castanheira Immunethep, Portugal | TNA beneficiary |
| 10:05 | Probing the mechanism of the peroxiredoxin decamer interaction with its reductase sulfiredoxin from the single molecule to the solution scale Hortense Mazon Nancy, France | Selected poster |
| 10:20 | Use of Monolith to measure affinity of antibodies to a trimeric membrane protein Pierre Soule Nanotemper | Company presentation |
| 10:30 | Quantify and characterize any protein interaction – even in complex backgrounds, even with challenging targets Sebastian Fiedler Fluidic Analytics | Company presentation |
| 10:40 | Coffee break | |
| SESSION 4 Architecture of macromolecular assemblies, allostery and protein dynamics | ||
| Organisers: EPR-MRS, CNRS & Aix-Marseille University, Marseille, FR and Pasteur-PFBMI, Institut Pasteur, Paris, FR | ||
| Chair(s): Pierre DORLET (EPR-MRS) and Bertrand RAYNAL (Pasteur-PFBMI) | ||
| 11:15 | Role of allostery and oligomerization in tuning one-component systems controlling bacterial biofilm maintenance Serena Rinaldo Sapienza Università di Roma, Italy | Talk |
| 11:40 | The role of highly dynamic regions from PP2A inhibitors in orchestrating the binding to respiratory cytochrome c Irene Díaz-Moreno Universidad de Sevilla, Spain | Talk |
| 12:05 | Investigating the Interactions Between Myc and the RNA Polymerase II Component TFIIF Tristan Kenney University of Toronto, Canada | TNA beneficiary |
| 12:20 | Single-molecule fluorescence applications in protein amyloid aggregation: from basic research to diagnosis Nunilo Cremades Zaragoza, Spain | Selected poster |
| 12:35 | Fractionation and Characterization of Macromolecules and Nanoparticles: Solutions for Gene Vectors Nicolas Mignard Wyatt | Company presentation |
| 12:45 | Microfluidic Modulation Spectroscopy (MMS): Automated, Highly-Sensitive IR-Based Protein Structural Analysis in situ, Without the Fuss Patrick King RedShiftBio | Company presentation |
| 12:55 | lunch | |
| SESSION 5 Single molecule and time resolved analyses | ||
| Organisers: RUG-BP, Rijksuniversiteit Groningen, Groningen, NL and DSB-UROM – Sapienza University of Rome, Rome, IT | ||
| Chair(s): Francesca Cutruzzola (DSB-UROM), Wouter H. Roos (RUG-BP) | ||
| 14:00 | Protein-protein and protein-nucleic acid interactions in nucleotide metabolism Francesca Cutruzzola Sapienza Università di Roma, Italy | Talk |
| 14:25 | Single Molecule Manipulation and Imaging of complex DNA-protein interaction Gijs Wuite Vrije Universiteit, Amsterdam, the Netherlands | Talk |
| 14:50 | Insights into the Catalytic Mechanism of FdhAB from Desulfovibrio vulgaris Hildenborough Rita Rebelo Manuel ITQB NOVA – Universidade Nova de Lisboa, Portugal | TNA beneficiary |
| 15:05 | Investigation of lectin binding to SARS-CoV-2 spike glycans using single molecule force spectroscopy Joojin Oh Linz, Austria | Selected poster |
| 15:20 | Optical tweezers and single molecules: how to visualize and manipulate single biomolecules in real-time Vincenzo Mascoli Lumicks | Company presentation |
| 15:30 | Mass photometry – an analytical technology for biomolecular characterization James Wilkinson Refeyn | Company presentation |
| 15:40 | Coffee break | |
| SESSION 6 Membranes and condensates | ||
| Organisers: NIC, National Institute of Chemistry, Ljubljana, SI and ULB, Université Libre de Bruxelles, Brussels, BE | ||
| Chair(s): Gregor Anderluh (NIC) and Felix M. Goñi | ||
| 16:15 | Ceramide effects on lipid bilayer dynamics and structure Felix M. Goñi Biofísika Institute, Leioa, Spain | Talk |
| 16:40 | Modification of pore-forming toxins and their interactions with lipid membranes by directed evolution and insertion of non-canonical amino acids Ana Crnković National Institute of Chemistry, Ljubljana, Slovenia | Talk |
| 17:05 | Amyloid-Membrane interactions observed with OCD and FTIR Florian Turbant CEA and Univ Paris Cité, France | TNA beneficiary |
| 17:20 | Taylor-dispersion induced phase separation (TDIPS) for efficient characterisation of protein condensation Lars Boyens-Thiele Copenhagen, Denmark | Selected poster |
| 17:35 | Poster / networking session | |
| 20:00 | Congress dinner |
Wednesday 7th June 2023
| 08:30 | Welcome coffee | |
| SESSION 7 Molecular bioimaging | ||
| Organisers: LAMBS, Universita Degli Studi Di Genova, Genoa, IT | ||
| Chair(s): Claudio Canale (LAMBS) and Ornella Cavalleri (University of Genova, Italy) | ||
| 09:00 | Binding strategies of SARS-Cov-2 spike variants viewed on the single molecule level Peter Hinterdorfer Institut of Biophysics, Johannes Kepler University (JKU) Linz, Austria | Talk |
| 09:25 | From super-resolution to correlative microscopy, studying the effects of photosensitizers in cells and pathogens. Paolo Bianchini Istituto Italiano di Tecnologia, Genoa, Italy | Talk |
| 09:50 | Hyperspectral microscopy and ligand screening of TTR amyloid fibrils Marikken Sundnes NTNU, Trondheim, Norway | TNA beneficiary |
| 10:05 | Condensate Formation of Cell Division Proteins FtsZ and SlmA in Physiologically Relevant Glutamate Buffer and Its Time-Dependent Evolution on Lipid Surfaces Gianfranco Paccione Madrid, Spain | Selected poster |
| 10:20 | The SPR Pro Series – Information-Rich Assays at Full Flexibility Cyrill Brunner Bruker Daltonics | Company presentation |
| 10:30 | Pushing the limits of BLI: new biosensor technology for protein and AAV research T. Zbik I&L Biosystems | Company presentation |
| 10:40 | Group Photo | |
| 10:45 | Coffee break | |
| SESSION 8 Computational approaches in biophysics | ||
| Organisers: MoB-IBT, Institute of Biotechnology of the Czech Academy of Sciences, Vestec, CZ and AFFINImeter, Santiago de Compostela, ES | ||
| Chair(s): Emil Dandanell Agerschou (MoB-IBT) and Juan Sabin (AFFINImeter) | ||
| 11:15 | Shining a Light on Dynamic Data: From generation to interpretation Osvaldo Burastero EMBL Hamburg, Germany | Talk |
| 11:40 | Making integrative structures accessible through PDB-Dev: From single molecules to dynamic macromolecular assemblies Brinda Vallat RCSB PDB at Rutgers, The State university of New Jersey, USA | Talk |
| 12:05 | The story of KEIF, the assumed appendix that held on for dear life Amanda Eriksson Skog Division of Computational Chemistry, Lund University, Sweden | TNA beneficiary |
| 12:20 | Different enzymatic inhibitors trigger different IDO1 conformations that can influence its signaling functions Elisa Bianconi Perugia, Italy | Selected poster |
| 12:35 | Concluding remarks | |
| Lunch | ||
| 14:00 | MOSBRI General assembly MOSBRI partners only | |
