5) RUG-BP – Zernike Institute for Advanced Materials, Rijksuniversiteit Groningen

Location: Groningen, The Netherlands

MOSBRI reference site for the following techniques:
AFM: Atomic Force Microscopy, Optical Tweezers

Practical information:
View here.

Partner description

The RUG-BP infrastructure is located at the Zernike institute of the Rijksuniversiteit Groningen in the Netherlands and comprises the experimental biophysics efforts of the institute. RUG-BP has state-of-the-art equipment for all offered techniques and research output illustrates that we perform top-level research using these techniques. In particular the available techniques include Atomic Force Microscopy (AFM), Optical Tweezers, solid state NMR and fixed and life cell STED Super-resolution Microscopy.

Instruments / methodologies offered through TNA

  • (High Speed) AFM: We provide access to both traditional as well as High speed AFM. Measurements are predominantly performed in liquid.
    Refs: Nature Chemistry, ACS Nano, JACS
  • Optical Tweezers: With this set-up we are able to trap one or two beads and to measure/exert pN forces and nm displacements.
    Refs: Nano Letters, Science Advances
  • ssNMR: The solid state NMR set-up is used for a variety of experiments with a focus on studying self-assembly processes.
    Refs: Nature Communications, JACS 
  • STED microscopy: Our super resolution fluorescence microscopes are both used for fixed cell and life cell experiments.
    Refs: PNAS

Access modality: Access is typically provided as two weeks physical access.

Sample requirements

Full details of the sample requirements for each of the techniques offered at this TNA site can be found here.