ESC5: Label-free techniques for the characterization of protein interactions

Description of the course:

The course will be focused on the application of label-free biophysical techniques iTC, MST, and DSF for the characterization of protein interactions and will combine both theoretical and practical content.

Outline of the course:

The course will start on Wednesday 3^rd of May afternoon and end on Friday 5^th of May afternoon.

Day 1

Lunch

Lecture 1:       Introduction to iTC: principles and experimental design
Lecture 2:       Principles of MST technique, Label-Free MST, Differential scanning fluorimetry technique

Tour of the Centre of Molecular Structure facilities.

Day 2

Hands-on workshop in two groups of 5 participants.

1^st group – iTC
2^nd group – LF MST, DSF

Lunch

1^st group – LF MST, DSF
2^nd group – iTC

Day 3

Troubleshooting, data analysis, questions.

~ 1.5 hour 1^st group – iTC; 2^nd group – LF MST, DSF,
next 1.5 hours 1^st group – LF MST, DSF; 2^nd group – iTC.

Lunch.

Other details:

Participants will receive partial financial support to attend the course, including economy travel, lunches, dinners and 2 nights of accommodation with breakfast (accommodation will be booked by the organizers). Ten travel bursaries of a maximum 300 euros each will be offered to cover travel costs. Successful applicants will be informed of the eligible expenses when they receive a formal acceptance letter.

Download a pdf version of a flyer for this course via the link below:

MOSBRI-ESC5-Flyer.pdf

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Application to take part in the course

The course is limited to 10 participants and therefore any interested parties will need to submit an application for consideration to take part.

Who is eligible to apply:

Anyone with a workplace/host institution in one of the EU member or associated states may apply to attend this course (this includes people from the UK). Applicants from industry are also welcome. It is expected that the applicant has at least a basic knowledge of molecular biology, chemistry and/or biophysics and that it is applicable to their area of research/work. Applications from scientists in the early-stage of their career are particularly encouraged and we will strive to obtain a gender balance of the participants in the course.

How to apply:

When to apply:

It is no longer possible to apply for this course. The applications received are under review and applicants will be informed once a decision has been made.

Application deadline:

The deadline for submission of an application to participate in this course was the: 12^th March 2023.