Programme

The conference will open on Monday 20th of June at 14:00 and end on Wednesday 22nd of June at 12:30.

Delegates are invited to a cocktail dinner on the evening of the 20th of June.

The conference will take place at the Scientific Information Centre Auditorium – Institut Pasteur, Paris

15th June 2022: The full programme and abstract book is now available for download here

MOSBRI2022_BookOfAbstracts_InstitutPasteur-Paris_20-22June2022.pdf

19th July 2022: Many of the presentations given at the conference are now available to view online. To watch a presentation on YouTube, click on the title in the programme below.

Monday 20th June 2022

14:00  Opening/Welcome  
14:15  Pasteur-PFBMI : 20 years old and as dashing as ever!
Patrick England and Bertrand Raynal
Molecular Biophysics, Institut Pasteur, Paris, France
MOSBRI partner
14:45  Synchrotron radiation circular dichroism at MOSBRI partner AU-SRCD
Søren Vrønning Hoffmann
ISA, Department of Physics and Astronomy, Aarhus University, Aarhus, Denmark
MOSBRI partner
15:15 Characterization of the intrinsically disordered region of human NDRG1, a target for lung cancer therapy
Barbara Zambelli
Pharmacy and Biotechnology, University of Bologna, Bologna, Italy
TNA beneficiary
15:30 To affinity and beyond: New approaches to changing the paradigm in drug discovery
Paul Belcher
Cytiva, Malborough, United States
Sponsor
15:40 Light scattering solutions for the characterization of macromolecules
Stéphanie Terme-Ferrari
Wyatt Technology, France
Sponsor
15:50-16:30 Coffee break  
16:30 Biophysical studies of membrane pore formation by bactericidal perforin-2
Robert Gilbert
University of Oxford, UK
Scientific Advisory Board member
17:00 The EMBL SPC facility
Maria Garcia Alai and Osvaldo Burastero
EMBL HH, EMBL, Hamburg, Germany
MOSBRI partner
17:30 Combined use of diverse biophysical techniques for the investigation of repetitive extragenic palindromes (REPs) and their associated tyrosine transposases RAYTs
Tatsiana Charnavets and Jan Dohnalek
CMS, Institute of Biotechnology of the Czech Academy of Sciences, Vestec, Czech Republic
MOSBRI partner
18:00 The correlation of changes in metabolic and glycosylation pathways by the analysis of biophysical profiles of melanoma cells treated with the computationally predicted drug combinations
Anna Sobiepanek
Laboratory of Biomolecular Interactions Studies, Chair of Drug and Cosmetics Biotechnology, Faculty of Chemistry, Warsaw University of Technology, Poland
TNA beneficiary
18:15 Mass photometry – revolutionary biophysical characterization of single molecules
Tomás De Garay
Refeyn Ltd., Oxford, United Kingdom
Sponsor
18:25 OpenSPR & Alto: Nicoya’s Label-Free solutions for biologics research take the complexity out of SPR and empower your team with the data you need
Nicolas Carvou
Nicoya Lifesciences inc., Canada
Sponsor
18:35 – 21:30 Poster/networking session and cocktail dinner  

Tuesday 21st June 2022

08:30 Welcome coffee  
09:00 EPR-MRS site: EPR spectroscopy for the study of biomolecules
Pierre Dorlet
BIP UMR 7281, CNRS, AMU, Marseille, France
MOSBRI partner
09:30 Riboregulation of human serine hydroxymethyltransferase enzymatic activity reveals a novel strategy to shape cell metabolism
Francesca Cutruzzola

Department of Biochemical Sciences, Sapienza University of Rome, Italy
MOSBRI partner
10:00 Dynamics of microtubule-nucleated multimolecular tau assemblies
Adela Karhanova
Biotechnology Institute, BIOCEV, Vestec, Czech Republic
TNA beneficiary
10:15 heliX®: The Modular Biosensor for Measuring Interactions from small molecules to cells
Amandine Gontier
Dynamic Biosensors GmbH, Martinsried/planegg, Germany
Sponsor
10:25 Full control and versatility to allow the direct and real-time visualization of dynamic single-molecule processes essential to life
Kalthoum Ben M’barek
Lumicks, Amsterdam, The Netherlands
Sponsor
10:35-11:15 Coffee break  
11:15 Biophysics in Drug Discovery: the Past, Present, and the Future
Christine Genick
Novartis Pharma AG,Basel, Switzerland
Scientific Advisory Board member
11:45 Integrated Structural Biology as a Toolbox to Dissect Viral Entry
Eleonore Von Castelmur

Department of Physics, Chemistry and Biology, Linköping University, Sweden
MOSBRI partner
12:15 DGE-AUC: Adapting the Power of Density Gradient Separations for the Characterization-in-Solution by Analytical Ultracentrifugation
Michel Rouxel

BeckmanCoulter, Villepinte, France
Sponsor
12:25 Immunogenic affinity and extracellular vesicle quantification in whole blood with FO-SPR
Filip Delport
FOx Biosystems, Diepenbeek, Belgium
Sponsor
12:35-14:00 Lunch  
14:00 Biophysical characterization of viral and lipid-based vectors for vaccines and therapeutics with light scattering and calorimetric techniques
Natalia Markova
Malvern Panalytical, Malvern, United Kingdom
MOSBRI partner
14:30 Interactions between membranes and pore-forming toxins
Neža Omersa
Department of Molecular Biology and Nanobiotechnology, National Institute of Chemistry, Ljubljana, Slovenia
MOSBRI partner
15:00 Flexibility Meets Throughput: The SPR Pro Platform
Cyrill Brunner
Bruker Daltonics SPR, Fällanden, Switzerland
Sponsor
15:10 Fida 1: The Ultimate Biophysics Tool – Fast and accurate in-solution analysis of proteins and nanoparticles
Henrik Jensen
Fidabio, Copenhagen, Denmark
Sponsor
15:20-16:00 Coffee break  
16:00 AFFINImeter: A software to analyze molecular recognition processes from experimental data
Juan Sabin
AFFINImeter, Santiago De Compostela, Spain
MOSBRI partner
16:30 Automated STED nanoscopy allows to study cell division without synchronization and reveals how the assembly and constriction of ESCRT-III polymers aid archaeal cell divisiona
Rifka Vlijm

Zernike Institute, Rijksuniversiteit Groningen, The Netherlands
MOSBRI partner
17:00 Human Glucose-Regulated Protein 94 (GRP94): Protein Characterization and Functional Analysis
Hajira Ahmed Hotiana
Department of Biomedical Sciences, Membrane Protein Biology Group, University of Copenhagen, Denmark
TNA beneficiary
17:15 Pushing the Boundaries in Biomolecular Interaction Analysis with GCI and waveRAPID
Edward Fitzgerald

Creoptix, Wädenswil, Switzerland
Sponsor
17:25 Measure molecular interactions with Spectral Shift to minimize assay development time
Tanja Bartoschik
Nanotemper Technologies GmbH, Munich, Germany
Sponsor
17:35 With Octet® systems, you don’t have to choose between SPR and BLI
Christophe Quetard
Sartorius, Dourdan, France
Sponsor
17:45 – 20:00 Poster/networking session  
  Free evening  

Wednesday 22nd June 2022

08:30 Welcome coffee  
09:00 Multiple Perspectives on Multiple States
Mark Williams
Institute of Structural and Molecular Biology, Department of Biological Sciences, Birkbeck, University of London, United Kingdom
MOSBRI partner
09:30 Characterization of misfolded protein aggregates through AFM-STED correlative nanoscopy
Claudio Canale

Department of Physics, University of Genoa, Genova, Italy
MOSBRI partner
10:00 ARBRE: a Europe-wide connexion hub for molecular-scale biophysics research
Adriana Erica Miele
UMR 5280 Institut des Sciences Analytiques, Université Claude Bernard Lyon 1, Villeurbanne, France
Invited Speaker
10:30 Group photo  
10:35 – 11:15 Coffee break  
11:15 Infrared spectroscopy, a versatile tool
Vincent Raussens
Center for Structural Biology and Bioinformatics, Laboratory for Structure and Function of Biological Membranes, Faculty of Sciences, Université Libre de Bruxelles, Brussels, Belgium
MOSBRI partner
11:45 Protein stability and stabilization by ligands and by protein engineering: calorimetric and computational studies and tools
Javier Sancho and Adrian Velazquez Campoy
Institute for Biocomputation and Physics of Complex Systems, University of Zaragoza, Spain
MOSBRI partner
12:15 Concluding remarks  
12:30 End of the meeting and lunch boxes