An overview of the programme for the conference can be viewed below. As speakers are confirmed, details will be added to the programme. Here is some other practical information regarding the schedule of the conference.

  • The conference will open on at 14:00 on Monday the 5th of June and end at 12:30 on Wednesday the 7th of June.
  • The conference will take place at the Patio de la Infanta, Zaragoza.
  • Participants are invited to a conference dinner on the evening of the 6th of June.
  • For MOSBRI partners only, the general assembly will take place on the afternoon of the 7th June, starting at 14:00.

6th June 2023: The updated book of abstracts, including some practical information about the conference, is available for download. Last updated: 06/06-2023

Monday 5th June 2023

13:30Welcome coffee

SESSION 1: Protein stability, quality control and standards
Organisers: EMBL-SPC, EMBL, Hamburg, DE and AU-SRCD, Aarhus University, Aarhus, DK
Chair(s): María García (EMBL-SPC), Søren Vrønning Hoffmann (AU-SRCD, Aarhus, DK)
14:15Functional and structural characterization of Bone Morphogenetic Protein- 2 and the antagonist Noggin
Andre Matagne

University of Liège, Belgium
14:40How and why do we develop standard proteins?
Maelenn Chevreuil

Molecular Biophysics, Institut Pasteur, Paris, France
15:05Circular dichroism as a tool to monitor real-time structural changes in monoclonal antibody manufacture
Maria Gabriela Bruque

School of Biosciences, University of Birmingham, UK
TNA beneficiary
15:20Elucidating Interactions Between SARS-CoV-2 proteins
Jacek Plewka

Jagiellonian University, Poland
TNA beneficiary
15:35SUPR-DSF – Differential Scanning Fluorimetry for high-throughput protein stability screening
Jemma Roberts

Applied Photophysics
Company presentation
15:45Ultimate DSC : a new tool for protein characterization
Yannice Ricci

Company presentation
15:55Coffee break
SESSION 2 Redesigning Biomolecules to improve performance
Organisers: Malvern, Malvern, UK and BIFI-LACRIMA, University of Zaragoza, Zaragoza, ES
Chair(s): Natalia Markova (MALVERN) and Adrián Velázquez-Campoy (BIFI-LACRIMA)
16:30Tuning protein stability through charged mutations and multivalent excipients
Matja Zalar

University of Maribor, Slovenia
16:55Protein stabilization made simple: new bioinformatics tools for stability design
Javier Sancho

University of Zaragoza, Spain
17:20Characterization of the redox-centres in the electron-confurcating [FeFe]-Hydrogenase (HydABC) of Thermotoga maritima
Kilian Zuchan

Aix-Marseille Université, CNRS, France
TNA beneficiary
17:35Experimental evidence of intrinsic disorder and amyloid formation by the Henipavirus W proteins
Giulia Pesce

Marseille, France
Selected poster
17:50Specific Extracellular Vesicle detection and isolation in complex samples using FO-SPR
Kris Ver Donck

Fox Biosystems
Company presentation
18:00How to characterize the mode of action and avidity effects of antibodies using switchSENSE® and RT-IC
Amandine Gontier

Dynamic Biosensors
Company presentation
18:10Poster / networking session and cocktail dinner

Tuesday 6th June 2023

08:30Welcome coffee
SESSION 3 Macromolecular interactions: kinetics and thermodynamics
Organisers: ISMB-BIOPHYSX, Birkbeck College, University of London, London, UK and BIFI-LACRIMA, University of Zaragoza, Zaragoza, ES
Chair(s): Mark Williams (ISMB-BIOPHYSX) and Maria Sunnerhagen (ProLinC)
09:00Intrinsically disordered regions in proteins: Implications for physiology and drug discovery
Adrián Velázquez-Campoy

University of Zaragoza, Spain
09:25Four different biophysical methods and simulations reveal that protein quaternary structures in solution are a mixture of multiple forms
Gideon Schreiber

Weizmann Institute of Science, Israel
09:50Characterization of the interaction of monoclonal antibodies with bacterial GAPDH
Pedro Castanheira

Immunethep, Portugal
TNA beneficiary
10:05Probing the mechanism of the peroxiredoxin decamer interaction with its reductase sulfiredoxin from the single molecule to the solution scale
Hortense Mazon

Nancy, France
Selected poster
10:20Use of Monolith to measure affinity of antibodies to a trimeric membrane protein
Pierre Soule

Company presentation
10:30Quantify and characterize any protein interaction – even in complex backgrounds, even with challenging targets
Sebastian Fiedler

Fluidic Analytics
Company presentation
10:40Coffee break
SESSION 4 Architecture of macromolecular assemblies, allostery and protein dynamics
Organisers: EPR-MRS, CNRS & Aix-Marseille University, Marseille, FR and Pasteur-PFBMI, Institut Pasteur, Paris, FR
Chair(s): Pierre DORLET (EPR-MRS) and Bertrand RAYNAL (Pasteur-PFBMI)
11:15Role of allostery and oligomerization in tuning one-component systems controlling bacterial biofilm maintenance
Serena Rinaldo

Sapienza Università di Roma, Italy
11:40The role of highly dynamic regions from PP2A inhibitors in orchestrating the binding to respiratory cytochrome c
Irene Díaz-Moreno

Universidad de Sevilla, Spain
12:05Investigating the Interactions Between Myc and the RNA Polymerase II Component TFIIF
Tristan Kenney

University of Toronto, Canada
TNA beneficiary
12:20Single-molecule fluorescence applications in protein amyloid aggregation: from basic research to diagnosis
Nunilo Cremades

Zaragoza, Spain
Selected poster
12:35Fractionation and Characterization of Macromolecules and Nanoparticles: Solutions for Gene Vectors
Nicolas Mignard

Company presentation
12:45Microfluidic Modulation Spectroscopy (MMS): Automated, Highly-Sensitive IR-Based Protein Structural Analysis in situ, Without the Fuss
Patrick King

Company presentation
SESSION 5 Single molecule and time resolved analyses
Organisers: RUG-BP, Rijksuniversiteit Groningen, Groningen, NL and DSB-UROM – Sapienza University of Rome, Rome, IT
Chair(s): Francesca Cutruzzola (DSB-UROM), Wouter H. Roos (RUG-BP)
14:00Protein-protein and protein-nucleic acid interactions in nucleotide metabolism
Francesca Cutruzzola

Sapienza Università di Roma, Italy
14:25Single Molecule Manipulation and Imaging of complex DNA-protein interaction
Gijs Wuite

Vrije Universiteit, Amsterdam, the Netherlands
14:50Insights into the Catalytic Mechanism of FdhAB from Desulfovibrio vulgaris Hildenborough
Rita Rebelo Manuel

ITQB NOVA – Universidade Nova de Lisboa, Portugal
TNA beneficiary
15:05Investigation of lectin binding to SARS-CoV-2 spike glycans using single molecule force spectroscopy
Joojin Oh

Linz, Austria
Selected poster
15:20Optical tweezers and single molecules: how to visualize and manipulate single biomolecules in real-time
Vincenzo Mascoli

Company presentation
15:30Mass photometry – an analytical technology for biomolecular characterization
James Wilkinson

Company presentation
15:40Coffee break
SESSION 6 Membranes and condensates
Organisers: NIC, National Institute of Chemistry, Ljubljana, SI and ULB, Université Libre de Bruxelles, Brussels, BE
Chair(s): Gregor Anderluh (NIC) and Felix M. Goñi
16:15Ceramide effects on lipid bilayer dynamics and structure
Felix M. Goñi

Biofísika Institute, Leioa, Spain
16:40Modification of pore-forming toxins and their interactions with lipid membranes by directed evolution and insertion of non-canonical amino acids
Ana Crnković

National Institute of Chemistry, Ljubljana, Slovenia
17:05Amyloid-Membrane interactions observed with OCD and FTIR
Florian Turbant

CEA and Univ Paris Cité, France
TNA beneficiary
17:20Taylor-dispersion induced phase separation (TDIPS) for efficient characterisation of protein condensation
Lars Boyens-Thiele

Copenhagen, Denmark
Selected poster
17:35Poster / networking session

20:00Congress dinner

Wednesday 7th June 2023

08:30Welcome coffee
SESSION 7 Molecular bioimaging
Organisers: LAMBS, Universita Degli Studi Di Genova, Genoa, IT
Chair(s): Claudio Canale (LAMBS) and Ornella Cavalleri (University of Genova, Italy)
09:00Binding strategies of SARS-Cov-2 spike variants viewed on the single molecule level
Peter Hinterdorfer

Institut of Biophysics, Johannes Kepler University (JKU) Linz, Austria
09:25From super-resolution to correlative microscopy, studying the effects of photosensitizers in cells and pathogens.
Paolo Bianchini

Istituto Italiano di Tecnologia, Genoa, Italy
09:50Hyperspectral microscopy and ligand screening of TTR amyloid fibrils
Marikken Sundnes

NTNU, Trondheim, Norway
TNA beneficiary
10:05Condensate Formation of Cell Division Proteins FtsZ and SlmA in Physiologically Relevant Glutamate Buffer and Its Time-Dependent Evolution on Lipid Surfaces
Gianfranco Paccione

Madrid, Spain
Selected poster
10:20The SPR Pro Series – Information-Rich Assays at Full Flexibility
Cyrill Brunner

Bruker Daltonics
Company presentation
10:30Pushing the limits of BLI: new biosensor technology for protein and AAV research
T. Zbik

I&L Biosystems
Company presentation
10:40Group Photo

10:45Coffee break
SESSION 8 Computational approaches in biophysics
Organisers: MoB-IBT, Institute of Biotechnology of the Czech Academy of Sciences, Vestec, CZ and AFFINImeter, Santiago de Compostela, ES
Chair(s): Emil Dandanell Agerschou (MoB-IBT) and Juan Sabin (AFFINImeter)
11:15Shining a Light on Dynamic Data: From generation to interpretation
Osvaldo Burastero

EMBL Hamburg, Germany
11:40Making integrative structures accessible through PDB-Dev: From single molecules to dynamic macromolecular assemblies
Brinda Vallat

RCSB PDB at Rutgers, The State university of New Jersey, USA
12:05The story of KEIF, the assumed appendix that held on for dear life
Amanda Eriksson Skog

Division of Computational Chemistry, Lund University, Sweden
TNA beneficiary
12:20Different enzymatic inhibitors trigger different IDO1 conformations that can influence its signaling functions
Elisa Bianconi

Perugia, Italy
Selected poster
12:35Concluding remarks

14:00MOSBRI General assembly
MOSBRI partners only