MOSBRI: Molecular Biophysics to understand life and disease

MOSBRI Special Session at FEBS2024, 15:30-16:00, 1st July 2024, Milan.

MOSBRI: Molecular Biophysics to understand life and disease.
15:30 – 15:45 Patrick England, Institut Pasteur, Paris, France.
15:45 – 16:00 Francesca Cutruzzolà, Sapienza University, Rome, Italy.

The pan-European MOlecular-Scale Biophysics Research Infrastructure MOSBRI (mosbri.eu) was launched in 2021 to provide free-of-charge trans-national access (TNA) to cutting-edge instrumentation and expertise in molecular biophysics through an integrated consortium including partners from 11 European countries, thus enabling excellent life science research. In this special session, we will highlight success stories selected from the more than 150 TNA projects accepted to date from applicants worldwide, and showcase some of the networking activities (international conferences, courses and training schools) and joint research activities that MOSBRI has spearheaded.

 

FEBS2024 programme

48th FEBS Congress, Milan

The 48th FEBS Congress – ‘Mining biochemistry for human health and well-being’ – will be hosted in Milano, Italy, from the 29th of June 29 to the 3rd of July 2024, for scientists from all over Europe and other parts of the world. The Italian Society of Biochemistry and Molecular Biology (SIB), founded in 1951, will be the host Society of the event.

The 48th FEBS Congress will present a broad-spectrum and ground-breaking scientific program, completed in a fruitful collaboration with the journals of FEBS and representatives from FEBS Constituent Societies. The focus on human health and well-being, through molecular and cellular science approaches, reflects a key social issue and a specific commitment of SIB and the whole biochemical community in a time of ongoing global transitions. Besides important research topics following the latest and emerging developments in the biochemical sciences, the Congress activities will include dedicated education-oriented sessions, symposia organized by young biochemists, and biochemistry-related economic discussions. There will also be opportunities for presentations from industry of the latest advances in commercial instrumentation.

Read more about the congress and register here.

ESAB 2024: European South Atlantic Biophysics Congress

the European South Atlantic Biophysics Congress that will take place in Donostia-San Sebastian (Basque Country), on June 5th-7th , 2024. The event will include a Satellite Workshop on June 4th-5th, 2024, focused on early-stage researchers, with a total attendance of 50 students.
The meeting is being organized as a joint effort by the Spanish Biophysical Society (SBE), the French Biophysical Society (SBF) and the Portuguese Biophysical Societies (SPBf), to gather scientists for presenting their most exciting biophysical research work.

The main Local Organizer, CIC biomaGUNE, is managing the preparation of the ESAB 2024 Congress in collaboration with local institutions such as Donostia International Physics Center, CIC bioGUNE, Instituto Biofísica and the University of Basque Country UPV/EHU.

This congress is the first event of a regional agreement between the three societies in order to organize periodic conferences promoting biophysics, especially amongst young scientist in the South-West of Europe. This congress will be an excellent opportunity for researchers to meet and discuss opportunities to collaborate in a genuinely multidisciplinary environment in the field of Biophysics. We hope that the participation of three societies will broaden the networking activities and the dissemination of knowledge in biophysics.

Visit the website to find out more about the congress and to register.

https://www.biophysicssansebastian2024.com/

Course on Protein Quality Control

This course is organized by Prof. André Matagne, Laboratory of Enzymology and Protein Folding, Centre for Protein Engineering, University of Liège, Belgium, on behalf of the F.R.S.-FNRS Graduate School “Structure and Function of Biological Macromolecules, Bioinformatics and Modelling” and the Belgian Biophysical Society.

Purified proteins stand as a central focus in numerous research laboratories, where they are used for a wide spectrum of applications ranging from 3D structural analysis, through X-ray, cryoEM, and NMR studies, to in-depth investigations into interactions (protein-protein, protein-ligand, or protein-nucleic acid) and cell biology experiments. Furthermore, these proteins play a crucial role in characterizing biological (e.g. enzymatic) activities. Beyond the realm of academic research, purified proteins serve as efficient tools in the therapeutic and diagnostic landscape, finding applications in various pharmaceutical industries. To ensure the reliability of experimental data in these studies, stringent protein quality controls are imperative. In 2021, the collaborative efforts of the ARBRE-MOBIEU and P4EU networks resulted in the publication of comprehensive guidelines for evaluating purified proteins in life sciences and medical trials (de Marco et al., 2021; Berrow et al., 2021). The objective of this course is to familiarize participants with these guidelines for protein quality control and to provide an overview of the technologies essential for enhancing the accuracy and reproducibility of data obtained with purified proteins. Throughout the course, participants will have access to the theoretical foundations of these technologies and will also gain hands-on experience with them, ensuring a comprehensive learning experience.

Read more about the course and apply here:
https://www.cip.uliege.be/cms/c_12068241/en/course-on-protein-quality-control

The deadline for applications is: 15th March 2024.

BLS2: Techniques to study single molecule/particle interactions

Scientific Organizers:
Zdenek Lansky (Institute of Biotechnology, Czech Academy of Sciences, Prague)
Carsten Janke (Institut Curie, Orsay, France)

Single molecule imaging techniques enable following bio-molecular interactions with unprecedented resolution. Following single molecules in cells is often challenging due to the complex geometry of the intracellular environment. By contrast, in in vitro reconstituted systems, comprising only few bio-molecules of interest, single molecule imaging is achievable e.g. by placing the sample in close vicinity of a glass surface and using Total Internal Reflection Fluorescence (TIRF) microscopy. However, the main obstacle of this method is obtaining functional bio-molecular samples in high enough quantity and purity. During the Basic Level School, we will explore an experimental approach combing the best of the two worlds by imaging bio-molecular interactions with single molecule resolution in cell lysates. This method employs the usage of established in vitro methods, such as TIRF imaging, while not being dependent on laborious sample preparation, and, importantly, enables following single molecule dynamics in the presence of other cellular components.

This MOSBRI basic level school (BLS2) held at MOSBRI partner MoB-IBT. For more details about this school, including how to apply, visit the webpage for the school.

Real-time monitoring using biophysical approaches of respiratory activity in bacteria

This consensus meeting aims to outline and define novel frontiers of the real-time techniques for monitoring respiratory and metabolic activities in bacteria, using biophysical methods.

Through a series of talks featuring expert speakers and a roundtable discussion, the event will combine expertise from manufacturers alongside academia. The primary objective is to define, project, and establish benchmarks for these monitoring techniques.

While the applications span diverse domains such as physiopathologic analysis and antimicrobial identification, critical questions remain open. These encompass the precision of real-time monitoring, its scalability across bacterial species, and the translation of laboratory findings into clinical or industrial settings.

Read more and register for this consensus meeting here.

XXVIII School of Pure and Applied Biophysics

The “XXVIII School Of Pure and Applied Biophysics”, organized by the Italian Society of Pure and Applied Biophysics (SIBPA) in collaboration with the Istituto Veneto di Scienze Lettere e Arti (IVSLA), will take place the 5th to 9th of February 2024 at Palazzo Franchetti in Venice.

This year’s theme, “Molecules in(ter)action: from nano to macroscale” will span from cuvette experiments to in vivo, exploring the fascinating world of biomolecular interactions from physics perspective.

The aim of this course is to delve into the structure, conformation, dynamics, and interactions of biomolecules in diverse environments, from solutions to living cells and biological tissues. We will explore a range of experimental techniques for tracking both in vitro and in vivo biochemical reactions and other processes crucial to life.

Applications are welcome from young scientists, including PhD students and postdocs, who share an interest in the subject matter of the school. An opportunity to present your work will be provided through a poster session and flash talks. Registration guidelines can be found on the school’s website at the link below . Please note that due to limited seating, only a maximum of 26 participants will be selected by the Scientific Committee based on the information provided in your application, including a short CV and a recommendation letter. Seats are filling up fast, so don’t delay!

The application deadline is the 16th of December 2023.

We look forward to your active participation in this enriching educational experience. For further details and application instructions, visit the school website.

https://venice2024.ibf.cnr.it/

XXIII Annual Linz Winter Workshop

The XXIII. Annual Linz Winter Workshop will be held at the University of Linz, Austria and will focus on
biological single-molecule research, nano-science, nano-medicine, cell-science and bio-nanotechnology and
include force and optical microscopy/spectroscopy techniques. This year, special sessions on nano-medicine
and high-speed atomic force microstcopy will be organized.

More information about the workshop can be found at
https://www.jku.at/institut-fuer-biophysik/veranstaltungen/linz-winterworkshop/

Note that the deadline for registration for this workshop has been extended to the 15th of December 2023.